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    January 1987 in “ Veterinary Dermatology
    Kjell Granström, Karolina Olsson
    TLDR Topical 0.1% tacrolimus improved a rare ear condition in cats.
    The document described a rare condition called proliferative and necrotizing feline otitis externa, diagnosed in three adult domestic shorthair cats and one kitten. The condition involved large plaques and exudate in the ear canals, leading to secondary infections. Despite initial treatments with antibiotics and corticosteroids, the condition persisted. Histological examination revealed specific changes in the hair follicles. Treatment with topical 0.1% tacrolimus led to marked improvement in the adult cats, with complete resolution in some cases, although one cat was lost to follow-up.
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