Effect of Exogenous Testosterone, Finasteride, and Castration on Serum Level of Thyroxin

The study investigated the effects of testosterone, finasteride, and castration on serum thyroxin (T4) levels and body metrics in male rats. It involved 32 rats divided into four groups: control, castration, finasteride, and testosterone. After 35 days, results showed that body weight increased in castrated rats and decreased in those given testosterone, with no significant change in the finasteride group. Prostate weight increased with testosterone and decreased with castration and finasteride, while testis weight remained unchanged across groups. Serum T4 levels decreased in all experimental groups, indicating that both high and low testosterone levels reduced T4 in a time-dependent manner.