Tofacitinib Therapy for the Treatment of Alopecia Areata: Report of 11 Patients

August 2019 in “ Journal of the American Academy of Dermatology ”

Tofacitinib alopecia areata Janus kinase inhibitor autoimmune condition

TLDR Tofacitinib may help hair regrowth in alopecia areata, but more research is needed.

The document reported on the use of Tofacitinib therapy for treating alopecia areata in a study involving 11 patients. The study aimed to evaluate the effectiveness of Tofacitinib, a Janus kinase inhibitor, in promoting hair regrowth in individuals with this autoimmune condition. The results indicated that Tofacitinib showed promise as a treatment option, with several patients experiencing significant hair regrowth. However, the small sample size of 11 patients suggested that further research with a larger cohort was necessary to confirm these findings and better understand the long-term efficacy and safety of Tofacitinib for alopecia areata.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community What else is good. Besides the big 3.

in Chat 35 upvotes 1 year ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community 22F. Should I even bother getting a biopsy? Is there any point?

6 upvotes 9 years ago

A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

community IGE Hair Loss and Miniaturization

in Chat 3 upvotes 10 months ago

A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 1 year ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community The shedding caused by Minoxidil is one of the worst things. 2 months apart each picture

in Progress Pictures 290 upvotes 1 year ago

The conversation discusses the severe shedding caused by Minoxidil, with users sharing their experiences and outcomes. Some report eventual regrowth, while others see no improvement or worsening hair loss.

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7 / 7 results

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research PUVA Treatment of Alopecia Areata Totalis and Universalis: A Retrospective Study

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