Tofacitinib Treatment in Patients With Active COVID-19 Infection

    September 2021 in “ Curēus ”
    Abdulmajeed Alajlan, Lama Alzamil, Amal M Aseri
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    TLDR Tofacitinib may be safe for COVID-19 patients with alopecia without worsening symptoms, based on two cases.
    The document discusses the use of tofacitinib, a JAK1 and JAK3 inhibitor, in treating alopecia areata, an autoimmune disorder causing hair loss. Tofacitinib has been shown to be effective in promoting hair regrowth in patients with this condition. Despite concerns about potential immunosuppression during active COVID-19 infections, the document reports on two cases where patients with alopecia universalis continued their tofacitinib treatment without experiencing any worsening of their COVID-19 symptoms. This suggests that tofacitinib may be safely used without adverse effects on the course of COVID-19, although the sample size is very small with only two cases.
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      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 10 months ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community Topical solution recommendation

      in Treatment  2 upvotes 6 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Topical solution recommendation

      in Product  1 upvotes 6 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community can someone help me identify these pls

      in Treatment 3 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community 22F. Should I even bother getting a biopsy? Is there any point?

       6 upvotes 9 years ago
      A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

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