This case report discusses a female patient with overlapping autoimmune disorders, Graham-Little-Piccardi-Lassueur Syndrome (GLPLS) and hidradenitis suppurativa (HS), characterized by scalp hair loss and follicular lesions. Traditional treatments were ineffective, so the patient was administered tofacitinib 5 mg twice daily. After six months, there was significant improvement in hair loss and resolution of lesions, with no recurrence or adverse events over a two-year follow-up. The report highlights the potential effectiveness of the JAK inhibitor tofacitinib in treating these challenging co-occurring conditions.
This case report discusses a female patient with overlapping autoimmune disorders, Graham-Little-Piccardi-Lassueur Syndrome (GLPLS) and hidradenitis suppurativa (HS), characterized by scalp hair loss and follicular lesions. Traditional treatments were ineffective, leading to the administration of tofacitinib 5 mg twice daily. After six months, the patient showed significant improvement in hair loss and resolution of lesions, with no recurrence or adverse events over a two-year follow-up. The report highlights the potential effectiveness of the JAK inhibitor tofacitinib in treating these challenging conditions.
5 citations
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September 2020 in “Proceedings - Baylor University. Medical Center” Tofacitinib successfully treated a woman's severe symptoms from a rare autoimmune condition.
January 2021 in “Anais do Congresso Brasileiro de Reumatologia 2020” Tofacitinib improved arthritis and partially improved hair loss in a lupus patient without side effects.
June 2023 in “Romanian Medical Journal” The case shows how hard it is to tell apart Multiple Autoimmune Syndrome from other similar autoimmune conditions, but correct diagnosis is key for treatment to work.
