Topical Allium Cepa Ethanol Extract Restores SOD and VEGF Without Increasing Hair Length in UV-B-Exposed Wistar Rats
TLDR Allium cepa extract restores skin health but doesn't affect hair growth.
The study investigated the effects of topical Allium cepa ethanol extract on cutaneous superoxide dismutase (SOD) and vascular endothelial growth factor (VEGF) in UV-B-exposed Wistar rats. Twenty male rats were divided into five groups, with some receiving varying concentrations of the extract. Results showed that UV-B exposure significantly reduced SOD and VEGF levels, but the extract restored these levels dose-dependently, with the 4% concentration exceeding normal VEGF levels by 33%. Despite biochemical improvements, hair length remained unchanged across all groups. The findings suggest that Allium cepa extract is a potent antioxidant and pro-angiogenic agent, though it does not affect hair length, indicating potential for further research in hair photoaging treatments.
