Two Cases of the Rare Cronkhite-Canada Syndrome

Cronkhite-Canada syndrome (CCS) was a rare, non-heritable condition characterized by gastrointestinal polyposis, dysgeusia, malnutrition, total alopecia, and onychodystrophia. This report detailed two Danish cases: an 88-year-old female and a 69-year-old male, both presenting with malnutrition, dyspepsia, vomiting, dysgeusia, and hair loss. Upper endoscopy revealed marked edema and polyposis in the stomach. Both patients developed colonic adenocarcinomas, which were surgically removed. Treatment included hyperalimentation, prednisolone, and azathioprine, leading to remission in both patients, with the first patient achieving total remission.