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GlossaryAzathioprine

immunosuppressive drug used to treat autoimmune diseases and alopecia

Azathioprine, also known by brand names such as Imuran, is an immunosuppressive medication commonly used to prevent organ rejection in transplant patients and to treat autoimmune conditions like rheumatoid arthritis and certain types of alopecia. It works by inhibiting the proliferation of immune cells, thereby reducing the immune system's activity and preventing it from attacking the body's own tissues.

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Research

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research Sequential Therapy for Diffuse Proliferative and Membranous Lupus Nephritis: Cyclophosphamide and Prednisolone Followed by Azathioprine and Prednisolone

80 citations , January 1995 in “The Nephron journals/Nephron journals”

The treatment was effective for lupus nephritis with manageable side effects.

research Efficacy and tolerability of azathioprine for neuromyelitis optica spectrum disorder: A systematic review and meta-analysis

54 citations , May 2019 in “Multiple Sclerosis and Related Disorders”

Azathioprine can help with relapses and disability in NMOSD but has more side effects and needs more research.

research Azathioprine

42 citations , January 1998 in “BioDrugs”

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

research Ovarian function after renal transplantation: comparison of cyclosporin A with azathioprine and prednisone combination regimens

21 citations , August 1984 in “BJOG An International Journal of Obstetrics & Gynaecology”

Ovarian function was similar in both treatment groups, but both caused excessive hair growth.

research Adverse Events Associated with Azathioprine Treatment in Korean Pediatric Inflammatory Bowel Disease Patients

16 citations , January 2013 in “Pediatric Gastroenterology Hepatology & Nutrition”

Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.

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Community Join

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community An arthritis drug that can be used for Alopecia.

in Research/Science 5 upvotes 4 years ago

An arthritis drug, baricitinib, is discussed as a potential treatment for autoimmune alopecia, not androgenetic alopecia. Ritlecitinib is also mentioned as a possible treatment for scarring alopecia.

community Spironolactone and pregnancy planning

in Female 2 upvotes 1 year ago

A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

community Betamethasone dipropionate 0.05 (sernivo spray)

in General 76 upvotes 1 year ago

A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 2 years ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community Xeljanz....the magic drug!!!

2 upvotes 7 years ago

A user experienced significant hair regrowth from Xeljanz after severe alopecia but can no longer afford it. They are seeking ways to obtain the medication despite its high cost and potential side effects.

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