Urinary Retention in Patients with BPH Treated with Finasteride or Placebo Over 4 Years

    April 2000 in “ European Urology ”
    Claus G. Roehrborn, Reginald C. Bruskewitz, G.C. Nickel, S. Glickman, C. A. Cox, R. Rox Anderson, Stanley J. Kandzari, R Herlihy, G. Kornitzer, B.T. Brown, H. Logan Holtgrewe, A. J. Taylor, Dayong Wang, Joanne Waldstreicher
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    TLDR Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.
    A study of 3,040 men with BPH symptoms and enlarged prostate glands found that finasteride reduces the risk of acute urinary retention and BPH-related surgery by 57% and 55%, respectively, compared to placebo over a period of 4 years. The study highlights the need for early intervention in managing BPH to prevent complications and improve quality of life. Prostate volume and PSA levels are significant factors in predicting urinary retention and surgery in patients who do not take finasteride.
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