Viewpoint 2

The document discussed hidradenitis suppurativa (HS), a chronic skin condition characterized by follicular occlusion and inflammation. The initial trigger for HS was identified as follicular retention by keratinized stratified squamous epithelium, leading to bacterial invasion and abscess formation. The study highlighted three phenotypes of HS lesions based on cytokeratin expression. Treatment focused on removing hyperkeratosis causes, with early and radical surgery recommended to minimize recurrence. Factors such as friction, deodorants, obesity, genetics, and hormones were considered potential contributors to HS. Smoking was noted to be more common in HS patients, suggesting smoking cessation as a beneficial measure.