Current Understanding of Vitiligo: A Comprehensive Literature Review

    March 2026 in “ International Journal of Innovative Technologies in Social Science ”
    Michał Stachel, Karol Józef Szkarłat, Maksymilian Szklarski, Jędrzej Sztajura, Szymon Targosz, Weronika Szymacha, Aleksandra Płecka, Ewa Maraszewska, Karol Zimnicki, Alicja Stępień
    TLDR Vitiligo is a systemic disease with psychological effects, and new treatments focus on personalized care.
    Vitiligo, affecting 0.5-2% of the global population, is now recognized as a systemic disease with significant psychological impacts. Recent research has elucidated its complex pathogenesis involving oxidative stress, genetic factors, and immune mechanisms, particularly the IFN-γ-chemokine axis. Advances in diagnostic techniques and the development of targeted therapies, such as Janus Kinase inhibitors like ruxolitinib, have improved treatment options. The modern management of vitiligo emphasizes a holistic approach, integrating precise diagnostics and individualized therapies to address both medical and psychological needs of patients.
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