Clinical Features and Treatment Options of Vogt-Koyanagi-Harada Disease

Vogt-Koyanagi-Harada (VKH) disease is a rare autoimmune disorder affecting melanocyte-rich tissues, with ocular involvement as its hallmark feature. Diagnosis relies on clinical criteria and advanced imaging techniques. Early treatment with high-dose corticosteroids, often combined with immunosuppressive agents, is crucial to prevent chronic complications. Biological therapies are effective for refractory cases. Advances in imaging and understanding of the disease have improved diagnosis and treatment, with future management potentially benefiting from novel targeted therapies and artificial intelligence for early detection and personalized treatment.