The Hair Loss Encyclopedia

The Wound Healing Effect of Callicarpa Nudiflora in Scalded Rats

May 2019 in “ Evidence-based Complementary and Alternative Medicine ”

Xuguang Zhang, Xiu-min Li, Xinxin Zhou, Yong Wang, Weiyong Lai, Ying Liu, Yu-chao Luo, Junqing Zhang

Callicarpa nudiflora CNE Silver sulfadiazine epidermis dermis TNF-α IL-10 TGF-β1 VEGF Samd3 Callicarpa nudiflora extract Silvadene skin wound healing

TLDR Callicarpa nudiflora extract speeds up wound healing in scalded rats.

The study investigated the wound healing effects of Callicarpa nudiflora extract (CNE) on scalded rats, involving 40 rats divided into five groups. The 20% CNE-treated group showed significant improvements in wound closure and healing, with almost complete healing by day 21, compared to the control group. Histopathological examination revealed a mildly hypertrophic epidermis and intact dermis in the CNE-treated group. The study suggested that CNE could be a promising alternative for wound treatment, with fewer side effects than traditional treatments like silver sulfadiazine, due to its ability to upregulate VEGF and downregulate TGF-β1 and Smad3, contributing to scar reduction.

View this study on downloads.hindawi.com →

Discuss this study in the Community →

Research cited in this study

1 / 1 results

Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation

research Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation

26 citations , September 2018 in “Colloids and Surfaces B: Biointerfaces”

A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.

Related Community Posts Join

0 / 0 results

— no results

Similar Research

5 / 15 results

Combination of an Engineered Lactococcus Lactis Expressing CXCL12 with Light-Emitting Diode Yellow Light as a Treatment for Scalded Skin in Mice

research Combination of an Engineered Lactococcus Lactis Expressing CXCL12 with Light-Emitting Diode Yellow Light as a Treatment for Scalded Skin in Mice

6 citations , July 2021 in “Microbial biotechnology”

The combined treatment with engineered bacteria and yellow LED light improved wound healing in mice.

Phytochemical Analysis And Antibacterial Activities Of Avicennia Marina (Forssk.) Vierh. Extracts Against Vancomycin-Resistant Enterococcus Faecium

research Phytochemical Analysis And Antibacterial Activities Of Avicennia Marina (Forssk.) Vierh. Extracts Against Vancomycin-Resistant Enterococcus Faecium

2 citations , September 2022 in “Advances in Environmental Biology”

Avicennia marina leaf extract can fight Vancomycin-resistant bacteria.

Mucosal TLR5 Activation Controls Healthspan and Longevity

research Mucosal TLR5 Activation Controls Healthspan and Longevity

1 citations , January 2024 in “Nature communications”

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

A Case Study of Khalitya (Hair Fall) - Ayurveda Perspective

research A Case Study of Khalitya (Hair Fall) - Ayurveda Perspective

September 2025 in “Journal of Ayurveda and Integrated Medical Sciences”

Bhringraj oil effectively reduces hair fall and related issues.

Clinical Evaluation of Bhringraj Capsule and Oil Along with Nasya in the Management of Khalitya with Special Reference to Hair-Fall

research Clinical Evaluation of Bhringraj Capsule and Oil Along with Nasya in the Management of Khalitya with Special Reference to Hair-Fall

September 2021 in “International Ayurvedic Medical Journal”

Bhringraj capsule and oil with Nasya effectively reduce hair fall and related symptoms.