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Did you mean Androstanediol Glucuronide?

GlossaryAndrostanediol Glucuronide

metabolite of dihydrotestosterone linked to hair loss and hirsutism

Androstanediol Glucuronide (3α-Diol G) is a metabolite of dihydrotestosterone (DHT), a potent androgen hormone. It is often measured in clinical settings to assess androgen activity in the body, as elevated levels can be associated with conditions like androgenic alopecia (hair loss) and hirsutism (excessive hair growth).

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research Evidence of Increased 3‐Alpha‐Androstanediol Glucuronide in Female Pattern Alopecia: A Cross‐Sectional Observational Study Evaluating Ovarian, Adrenal, and Peripheral Androgens

May 2026 in “International Journal of Dermatology”

Higher levels of 3α-diol G are linked to more severe female pattern hair loss.

research 3 alpha, 17 beta-androstanediol glucuronide in plasma. A marker of androgen action in idiopathic hirsutism.

179 citations , May 1982 in “The Journal of clinical investigation/The journal of clinical investigation”

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

Female Androgenic Alopecia: The 3 Alpha, 17 Beta-Androstanediol Glucuronide/Sex Hormone Binding Globulin Ratio as a Possible Marker for Female Pattern Baldness

research Female androgenic alopecia. The 3 alpha,17 beta-androstanediol glucuronide/sex hormone binding globulin ratio as a possible marker for female pattern baldness

13 citations , September 1986 in “Archives of Dermatology”

Women with more 3α,17β-androstanediol glucuronide compared to sex hormone binding globulin are more likely to have female pattern baldness.

research Is 3α, 17β-androstanediol-glucuronide a diagnostic marker in women with androgenic manifestations?

3 citations , January 1992 in “Gynecological Endocrinology”

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.

research Correlation of Serum 3α-Androstanediol Glucuronide with Acne and Chest Hair Density in Men

51 citations , November 1988 in “The Journal of Clinical Endocrinology & Metabolism”

Higher levels of a specific hormone are linked to more chest hair and acne in men.

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community The theory that explains everything. Please help me make this big!

in Research/Science 2451 upvotes 5 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 73 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community Sulforaphane Topical to Degrade DHT - For People Who Want to Try the Theory that Explains Everything

in Treatment 38 upvotes 5 years ago

A user suggests making a potent sulforaphane topical to degrade DHT and promote hair growth. Another user notes that sulforaphane's low molecular weight might also lower systemic DHT.

community How I started reversing Male Pattern Baldness naturally ?

in Question 10 upvotes 9 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

community risks with finasteride and dutasteride

in Research/Science 141 upvotes 1 year ago

Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

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