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Did you mean 3β-Hydroxysteroid Dehydrogenase?

Glossary3β-Hydroxysteroid Dehydrogenase

enzyme crucial for converting steroid precursors into active hormones

3β-Hydroxysteroid Dehydrogenase (3β-HSD) is an enzyme that plays a crucial role in the biosynthesis of all classes of hormonal steroids, including androgens, estrogens, and glucocorticoids. It catalyzes the conversion of Δ5-3β-hydroxysteroids to Δ4-3-ketosteroids, a key step in the production of hormones that regulate various physiological processes, including hair growth and skin health.

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Research

5 / 1000+ results

research A new compound heterozygous frameshift mutation in the type II 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) gene causes salt-wasting 3 beta-HSD deficiency congenital adrenal hyperplasia.

29 citations , January 1996 in “The Journal of Clinical Endocrinology & Metabolism”

A genetic mutation in a specific gene causes a salt-wasting condition in a Pakistani girl and her family.

research Effect of 3-Beta Hydroxysteroid Dehydrogenase on Serum Testosterone Level in Obese Women With Polycystic Ovary Syndrome

June 2025 in “Journal of Kufa for Chemical Sciences”

3βHSD2 is not useful for diagnosing PCOS.

research 17 beta-hydroxysteroid dehydrogenase 3 deficiency in the Mediterranean population.

46 citations , August 2006 in “PubMed”

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

research Enzymology of the hair follicle.

31 citations , August 2001 in “PubMed”

Hair follicles convert androgens, affecting hair loss patterns.

research The Use of Trilostane for the Treatment of Alopecia X in Alaskan Malamutes

15 citations , September 2005 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association”

Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.

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Community Join

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community The theory that explains everything. Please help me make this big!

in Research/Science 2451 upvotes 5 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community 2 months on minoxidil 5% GOOD RESULTS?

in Progress Pictures 3 years ago

Asteride into your routine In this conversation, the user Icy-Indication267 was asking when they should start finasteride to treat their hair loss, which had responded well to minoxidil after two months. Other users shared advice on incorporating micro-needling and topical finasteride into their routine for optimal results.

community "but it will hurt my gains bro"

in Satire 1309 upvotes 1 year ago

The conversation humorously discusses hair loss treatments like Minoxidil, Finasteride, and Dutasteride, and their effects on hair and muscle gains. Users debate effectiveness and side effects, mixing scientific approaches with jokes.

community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

in Update 38 upvotes 7 years ago

The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

community U/joaopassos444 , HATS OFF brother !!

in Research/Science 126 upvotes 5 years ago

A new hair loss treatment theory beyond minoxidil and finasteride is proposed, causing mixed reactions in the community, with some members eager to explore and support it, while others call for more research and evidence.

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