research Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors 17 citations , December 2015 in “Bioorganic & Medicinal Chemistry” 3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.
research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases 51 citations , May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Certain drugs that block specific enzymes can help treat prostate diseases.
research Nonclassic adrenal hyperplasia 55 citations , August 2008 in “Reviews in endocrine and metabolic disorders” Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.
research Effects of mitotane treatment on human steroid metabolism: implications for patient management 26 citations , July 2012 in “Endocrine Connections” Mitotane changes steroid breakdown, affecting cortisol availability.
research Intracrine androgen biosynthesis, metabolism and action revisited 131 citations , September 2017 in “Molecular and Cellular Endocrinology” The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
learn Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor