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      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

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      a potent but unapproved and potentially problematic topical anti-androgen

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      24M Fin stopped working after 4 years, is it over

      community 24M Fin stopped working after 4 years, is it over

      in General  92 upvotes 12 hours ago
      A 24-year-old experienced hair regrowth with finasteride, minoxidil, and ketoconazole but saw a significant shed after four years despite continued treatment and healthy habits. They stopped minoxidil after shaving their head, noticed dandruff disappeared, and are seeking advice for potential regrowth.

      community Should I be shedding months after starting treatment?

      in Chat  5 upvotes 1 day ago
      A 22-year-old male experiencing diffuse thinning started finasteride and 2% minoxidil 8 months ago, then switched to 5% minoxidil with tretinoin 4 months ago. Despite initial improvement in hair density, he is now experiencing increased hair shedding, losing 100-200 hairs daily.

      community ISO a topical without minoxidil

      in Finasteride/Dutasteride  3 upvotes 1 day ago
      A user seeks a topical hair loss treatment without minoxidil, considering options like finasteride, dutasteride, caffeine, tretinoin, or prostaglandin analogues. Recommendations include products like Strut, Maximus, Zeuss, and custom formulas from compounding pharmacies.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science 1 day ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.