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    GlossaryAdrenal Androgens

    hormones from adrenal glands affecting hair growth and skin

    Adrenal androgens are hormones produced by the adrenal glands, which are located on top of the kidneys. These hormones, including dehydroepiandrosterone (DHEA) and androstenedione, play a role in the development of secondary sexual characteristics and can influence hair growth and skin health. While they are weaker than testosterone, they can be converted into more potent androgens or estrogens in the body.

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      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

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      community Thoughts about ORAL ketoconazole? (pills)

      in Ketoconazole 2 months ago
      Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

      community Bicalutamide effect on androgens?

      in Treatment  5 upvotes 5 years ago
      Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hair loss but may cause feminization. It is not recommended for those who do not want feminization effects.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  62 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community My Theory Of Androgenic Alopecia

      in Research/Science  17 upvotes 4 months ago
      Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.