learn Cyproterone
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
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5 / 801 resultslearn Baricitinib
JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases
learn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn Setipiprant
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
Research
5 / 1000+ results
research Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles
A protein called sFRP4 can slow down hair regrowth.
research A novel finasteride 0.25% topical solution for androgenetic alopecia: pharmacokinetics and effects on plasma androgen levels in healthy male volunteers
New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
research Immunologic adverse reactions of β-blockers and the skin (Review)
β-blockers can cause skin problems like psoriasis and vitiligo, and doctors should tell patients about these risks.
research A role for p75 neurotrophin receptor in the control of apoptosis‐driven hair follicle regression
The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
research A mechanical-assisted post-bioprinting strategy for challenging bone defects repair
The new method improves bone repair by enhancing cell loading and stability in bioprinted scaffolds.
Community Join
5 / 526 resultscommunity What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news
Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.
community A PSA for everyone in here dealing with shedding
Hair loss treatments like finasteride, minoxidil, and dutasteride require patience, as they can take months or years to show results, with initial shedding being common. Consistency is key, and unnecessary supplements should be avoided to prevent stress and impatience from worsening the situation.
community Did anastrozole make your hair worse even on a DHT blocker?
Combining anastrozole with finasteride/dutasteride may affect hair, as anastrozole prevents testosterone from converting to estrogen, potentially increasing DHT. Users suggest using the lowest effective dose of anastrozole.
community If you had to abandon DHT blockers, what’s next?
Users discuss alternatives to DHT blockers for hair loss, suggesting minoxidil, microneedling, natural DHT blockers, and scalp massages. Some explore RU58841, ketoconazole, hair transplants, and hair systems due to side effects from finasteride and dutasteride.
community After quitting min and fin I asked AI on how fix the mess I am in and it says:
Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.