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research Effect of disulfide bonds in human hair fibers on the melting behavior of their crystalline structure

March 2010 in “International Journal of Cosmetic Science”

Disulfide bonds affect the melting behavior of hair's crystalline structure, but hair retains some stability even after these bonds are broken.

research DSC-investigations of alpha-keratins and the specific effects of chemical treatments on human hair

January 2006

Chemical treatments weaken hair's thermal stability and structure.

research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond

2 citations , December 2008 in “Journal of Chemical Crystallography”

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

Enhanced Topical Delivery of Finasteride Using Glyceryl Monooleate-Based Liquid Crystalline Nanoparticles Stabilized by Cremophor Surfactants

research Enhanced Topical Delivery of Finasteride Using Glyceryl Monooleate-Based Liquid Crystalline Nanoparticles Stabilized by Cremophor Surfactants

47 citations , September 2013 in “Aaps Pharmscitech”

Improved hair loss treatment using special particles and surfactants.

research Development and evaluation of crystalline inclusion complex of finasteride using electrospraying as a novel approach

2 citations , July 2020 in “Journal of Drug Delivery Science and Technology”

Created finasteride complex to increase water solubility and drug release.

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community Alpha plus from Anagenica - 25%CB???

in Product 2 upvotes 2 years ago

A user ordered Alpha Plus from Anagenica, expecting it to contain specific percentages of Fin, Estradiol, Minoxidil, and CB0301. However, the received product's label showed different percentages, including a surprising 25% CB, leading the user to question its safety and accuracy.

community 17-alpha-estradiol/Alfatradiol how does it Work for Hair loss?

in Treatment 2 upvotes 1 year ago

17-alpha-estradiol may work for hair loss by inhibiting 5-alpha reductase, similar to finasteride. It might lower testosterone in the scalp, reducing DHT conversion.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

in Finasteride/Dutasteride 26 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community 5ar alpha reductase stimulation is different depending on whether it’s type 1 or 2

in Hair Systems 17 upvotes 3 years ago

The conversation discusses how different factors can stimulate type 1 and type 2 isoforms of 5-alpha reductase, which are enzymes linked to hair loss. Specific treatments mentioned include oral Dutasteride and topical Finasteride.

community Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid????

1 upvotes 7 years ago

The post discusses using a topical tincture containing zinc, azelaic acid, and other ingredients to inhibit 5 alpha-reductase activity for treating hair loss. The user plans to try this natural alternative before using finasteride or RU58841.

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