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GlossaryAmmonium Thioglycolate

chemical used in hair perming to break disulfide bonds

Ammonium Thioglycolate, also known as "Thio" or "Perm Salt," is a chemical compound commonly used in hair perming and straightening treatments. It works by breaking the disulfide bonds in the hair's keratin structure, allowing the hair to be reshaped into curls or straightened. This process is reversible, meaning the hair can return to its natural state over time or with additional treatments.

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research Quantitative Determination of Formaldehyde and Ammonium Thioglycolate (ATG) Allergen Levels as “Quality Markers” in Commercial Synthetic Braiding Hair Sold in Selected Cosmetic Beauty Shops in Kisii Town, Kenya

July 2026 in “Journal of the Kenya National Commission for UNESCO”

Synthetic braiding hair in Kisii Town contains formaldehyde, posing health risks.

research Effects of Thioglycolate Compounds in an Emerging Technique in the World of Cosmetics—Brow Lamination

2 citations , October 2024 in “Journal of Cosmetic Dermatology”

Thioglycolate compounds in brow lamination can cause skin irritation and other health issues.

research Protein loss in human hair from combination straightening and coloring treatments

18 citations , July 2015 in “Journal of cosmetic dermatology”

Straightening and coloring hair, especially with sodium hydroxide, greatly increases protein loss.

research Prospective ultramorphological characterization of human hair by optical coherence tomography

18 citations , August 2009 in “Skin Research and Technology”

OCT can identify hair structures, but chemical treatments can damage them.

research Chemical and physical treatments damage Caucasian and Afro‐ethnic hair fibre: analytical and image assays

15 citations , June 2019 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Chemical and physical treatments like bleaching, dyeing, and UV radiation damage both Caucasian and Afro-ethnic hair.

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