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GlossaryThioglycolic Acid

chemical used in hair treatments to break disulfide bonds

Thioglycolic Acid, also known as TGA, is a chemical compound commonly used in hair care products, particularly in hair perming and straightening treatments. It works by breaking the disulfide bonds in hair proteins, allowing the hair to be reshaped. This compound is also used in depilatory creams to remove unwanted hair by weakening the hair structure.

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Research

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research A Survey on Health Effects in a Human Population Exposed to Permanent‐Waving Solution Containing Thioglycolic Acid

31 citations , November 2003 in “Journal of Occupational Health”

Thioglycolic acid in hair products may pose reproductive and cancer risks for hairdressers.

Action of Thioglycolic Acid and L-Cysteine on Disulfide Cross-Links in Hair Fibers During Permanent Waving Treatment

research Action of Thioglycolic Acid and L-Cysteine to Disulfide Cross-Links in Hair Fibers during Permanent Waving Treatment

18 citations , January 2008 in “Sen'i Gakkaishi”

Thioglycolic acid and L-cysteine change hair structure differently during perms, affecting hair strength and curling efficiency.

research The location of the thioglycolic acid molecules in intrafibrillar unordered areas of the human hair keratin structure

10 citations , January 2012 in “International Journal of Cosmetic Science”

Thioglycolic acid mainly affects the unordered areas in hair structure.

Chemical Reactions in Curing Treatment for Permanent Hair Straightening Using Thioglycolic and Dithioglycolic Acids

research Chemical Reactions Occurring in Curing Treatment for Permanent Hair Straightening Using Thioglycolic and Dithioglycolic Acids

3 citations , January 2009 in “Sen'i Gakkaishi”

Using both TGA and DTDG in hair straightening reduces hair damage compared to using TGA alone.

Reproduction Mechanism of Disulfide Cross-Links in Permed Hair by Washing After Reduction with Thioglycolic Acid

research Reproduction Mechanism of SS Cross-Links in Permed Hair by the Washing after Reduction with Thioglycolic Acid

2 citations , January 2015 in “Sen'i Gakkaishi”

Washing permed hair after using thioglycolic acid helps reform strong bonds, making hair stronger.

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