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GlossaryAndrogen Exposure

body's interaction with male sex hormones like testosterone

Androgen exposure refers to the body's interaction with androgens, which are male sex hormones like testosterone. These hormones play a crucial role in the development of male characteristics and can influence hair growth patterns, potentially leading to conditions like androgenetic alopecia (male or female pattern baldness). For professionals, understanding androgen exposure is essential for diagnosing and treating hair loss and other androgen-related conditions.

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Research

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research Preservation of Fertility in Transgender Men on Long-Term Testosterone Therapy: A Systematic Review of Oocyte Retrieval Outcomes During and After Exogenous Androgen Exposure

16 citations , June 2022 in “Transgender Health”

Oocyte retrieval is possible for transgender men on testosterone therapy without affecting fertility outcomes.

research Polycystic ovary syndrome is associated with anogenital distance, a marker of prenatal androgen exposure

32 citations , February 2017 in “Human Reproduction”

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

research Effects of the prenatal and postnatal nurturing environment on the phenotype and gut microbiota of mice with polycystic ovary syndrome induced by prenatal androgen exposure: a cross-fostering study

3 citations , March 2024 in “Frontiers in Cell and Developmental Biology”

Prenatal and postnatal environments both affect PCOS development and gut microbiota in mice.

Digit-Length Ratios (2D:4D) as a Phenotypic Indicator of In Utero Androgen Exposure Is Not Prognostic for Androgenic Alopecia: A Descriptive-Analytic Study of 1200 Iranian Men

research Digit-length ratios (2D:4D) as a phenotypic indicator of in utero androgen exposure is not prognostic for androgenic alopecia: a descriptive-analytic study of 1200 Iranian men

3 citations , June 2016 in “Dermatology Reports”

Finger length ratios don't predict baldness in men.

In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome

research In vivo and in vitro exposure to free fatty acids induce increased androgen production in animal models: a potential pathogenic factor of the polycystic ovary syndrome

September 2008 in “Fertility and Sterility”

Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.

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Community Join

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community GT20029 Will Replace Finasteride For Hair Loss

in Research/Science 50 upvotes 2 months ago

GT20029 shows promise as a topical treatment for hair loss, potentially replacing finasteride for some due to its low systemic exposure and ability to degrade androgen receptors. However, skepticism remains about its long-term efficacy and availability, with some users expressing doubt about new treatments consistently failing to reach the market.

community Surprisingly thorough study on He-Shou-Wu/Fo Ti

in Research/Science 14 upvotes 3 years ago

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 3 years ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community For those that have used anti androgens what is your experience?

in Research/Science 16 upvotes 2 years ago

People discussed their experiences with anti-androgens for hair loss, mentioning side effects like chest pains with RU58841 and skepticism due to lack of safety data, while considering Fluridil as a potential addition to treatment. Some users expressed reluctance to use these chemicals.

community Has anyone powered through the creatine shedding (via increased androgen receptor sensitivity) and stabilized?

in Update 8 upvotes 11 months ago

Creatine may cause increased hair shedding due to androgen receptor sensitivity, despite limited evidence. The user is using dutasteride and minoxidil and seeks advice on whether shedding will stabilize, with suggestions including GHK-Cu and RU58841.

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Learn

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Epidermal Growth Factor

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