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GlossaryAndrogen Hypersecretion

excessive production of male sex hormones by endocrine glands

Androgen hypersecretion refers to the excessive production of androgens, which are male sex hormones like testosterone, by the body's endocrine system. This condition can lead to symptoms such as excessive hair growth (hirsutism), acne, and in severe cases, conditions like polycystic ovary syndrome (PCOS) in women. It can be caused by various factors, including adrenal gland disorders or tumors.

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research Hyposecretion of the adrenal androgen dehydroepiandrosterone sulfate (DHEA-S) in the majority of the alopecia areata patients: Is it a primitive and pathogenic perturbation of hypothalamic-pituitary-adrenal axis?

3 citations , January 2011 in “International journal of trichology”

Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.

Androgens and Erythropoiesis: Induction of Erythropoietin-Hypersecretory State and Effect of Finasteride on Erythropoietin Secretion

research Androgens and erythropoiesis. Induction of erythropoietin-hypersecretory state and effect of finasteride on erythropoietin secretion

10 citations , March 1999 in “Comparative Haematology International”

Androgens increase EPO production, finasteride doesn't significantly impact it.

Activation of Nuclear Factor κB in Response to Cream Ingestion Is Related to Ovarian Androgen Hypersecretion in Polycystic Ovary Syndrome

research Activation of nuclear factor κB in response to cream ingestion is related to ovarian androgen hypersecretion in polycystic ovary syndrome

6 citations , August 2013 in “Fertility and Sterility”

Eating cream can increase ovarian androgen production in women with Polycystic Ovary Syndrome, which is not related to obesity.

Androgenic Alopecia in Females: Diagnosis and Treatment

research Androgenic Alopecia

14 citations , July 1987 in “Dermatologic Clinics”

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

research Case Report: A Virilizing Adrenal Oncocytoma

6 citations , March 2021 in “Frontiers in surgery”

A woman's symptoms of increased body hair and testosterone were caused by a rare adrenal tumor, which was removed successfully.

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community Androgen degraders for hair loss

in Research/Science 61 upvotes 1 year ago

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

community Anti-androgen use causing testicular pain?

in Finasteride/Dutasteride 5 upvotes 11 months ago

Switching from topical finasteride to oral Dutasteride and using Fluridil caused persistent testicular discomfort. The discomfort did not subside after stopping Fluridil, raising concerns about Dutasteride's role.

community anti-androgens help with chronic seborric dermatitis ?! and hence diffuse thinning

in Finasteride/Dutasteride 7 upvotes 1 year ago

An 18-year-old experiencing hair loss and seborrheic dermatitis has tried finasteride, dutasteride, and various shampoos without success. They are considering anti-androgens like RU58841 and KX-826 for oil control and dandruff reduction.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community Anti androgen shed all over scalp

in Treatment 3 upvotes 2 years ago

The user is experiencing intense hair shedding all over the scalp after applying pyrilutamide to the hairline and taking oral castor oil. They are also using topical finasteride and latanoprost, but are unsure which treatment is causing the shedding.

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