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GlossaryCutaneous Hyperandrogenism

excess male hormones in skin causing hair growth and acne

Cutaneous Hyperandrogenism refers to a condition where there is an excess of androgens (male hormones) in the skin, leading to symptoms such as excessive hair growth (hirsutism), acne, and oily skin. This condition is often associated with disorders like polycystic ovary syndrome (PCOS) and can affect both men and women, though it is more commonly diagnosed in women.

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Research

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research Evidence-based approach to cutaneous hyperandrogenism in women

42 citations , July 2015 in “Journal of The American Academy of Dermatology”

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

research Cutaneous hyperandrogenism: role of antiandrogen therapy in acne, hirsutism, and androgenetic alopecia.

3 citations , November 2013 in “PubMed”

The Efficacy of Oral Isotretinoin Versus Cyproterone Compound in Female Patients With Acne and the Triad of Cutaneous Hyperandrogenism: A Randomized Clinical Trial

research The efficacy of oral isotretinoin versus cyproterone compound in female patients with acne and the triad of cutaneous hyperandrogenism: A randomized clinical trial

2 citations , January 2014 in “Advanced Biomedical Research”

Oral isotretinoin and cyproterone compound are equally effective for treating acne in women with cutaneous hyperandrogenism.

research COMPARING THE EFFECTIVENESS OF ORAL ISOTRETINOIN AND CYPROTERONE COMPOUND IN ACNE TREATMENT AMONG ADULT FEMALES WITH CUTANEOUS HYPERANDROGENISM: A PROSPECTIVE STUDY.

January 2024

Isotretinoin is recommended for acne treatment as it is as effective as cyproterone compound.

An Updated Clinico-Investigative Approach to Diagnosis of Cutaneous Hyperandrogenism in Relation to Adult Female Acne, Female Pattern Alopecia, and Hirsutism: A Primer for Dermatologists

research An Updated Clinico-investigative Approach to Diagnosis of Cutaneous Hyperandrogenism in relation to adult female acne, female pattern alopecia & hirsutism a primer for dermatologists

December 2023 in “Expert Review of Endocrinology & Metabolism”

New methods help diagnose skin conditions caused by too much male hormone in women, like acne, hair loss, and excess hair growth.

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Community Join

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community Topical androgens for alopecia to treat sebum overproduction on the face

in Product 1 upvotes 2 years ago

The conversation discusses using scalp antiandrogens like RU58841, pyrilutamide, or fluridil on the face to reduce sebum production, noting that clascoterone (winlevi) is an approved facial antiandrogen with underwhelming reviews.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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Learn

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learn RU58841

a potent but unapproved and potentially problematic topical anti-androgen

learn Fluridil

a topical anti-androgen with less systemic involvement

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Clinics

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26
Hair Loss Treatments
DCSI - Dermatology & Cutaneous Surgery InstituteWellington, FL · US

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