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GlossaryAndrogen Receptor Gene

encodes a protein that binds male hormones like testosterone

The Androgen Receptor Gene (AR Gene) is a gene located on the X chromosome that encodes the androgen receptor, a protein that binds to androgens, which are male hormones like testosterone. This receptor plays a crucial role in the development and maintenance of male characteristics, and mutations in the AR gene can lead to conditions such as androgen insensitivity syndrome and contribute to hair loss disorders like androgenetic alopecia.

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Research

5 / 1000+ results

A Variant of the Glucocorticoid Receptor Gene Is Not Associated with Adrenal Androgen Excess in Women with Polycystic Ovary Syndrome

research A variant of the glucocorticoid receptor gene is not associated with adrenal androgen excess in women with polycystic ovary syndrome

20 citations , December 2000 in “Fertility and Sterility”

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

research Novel Androgen Receptor Gene Variant Containing a Premature Termination Codon in a Patient with Androgen Insensitivity Syndrome

1 citations , August 2019 in “Journal of pediatric & adolescent gynecology”

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

research Evidence for two independent functional variants for androgenetic alopecia around the androgen receptor gene

26 citations , September 2010 in “Experimental Dermatology”

Two gene areas linked to male pattern baldness found, more research needed.

research The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene

December 2023 in “JCEM case reports”

A new gene variant causes glucocorticoid resistance in a mother and son.

Androgen Receptor Genetic Variant Predicts COVID-19 Disease Severity: A Prospective Longitudinal Study of Hospitalized COVID-19 Male Patients

research Androgen receptor genetic variant predicts COVID‐19 disease severity: a prospective longitudinal study of hospitalized COVID‐19 male patients

26 citations , September 2020 in “Journal of the European Academy of Dermatology and Venereology”

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

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Community Join

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community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Male pattern baldness is not cosmetic.

in Chat 223 upvotes 7 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

community Rate my MPB Genetics: Can I run Primobolan/Masteron? (Detailed MyHeritage DNA Data Included)

in General 262 upvotes 3 months ago

The user is using testosterone and finasteride to prevent hair loss and is considering adding Primobolan or Masteron, which are DHT-derivatives. They are seeking advice on their genetic risk for male pattern baldness and whether they can safely use these compounds without significant hair loss.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community So many horror stories about switching from fin to dut

in Finasteride/Dutasteride 58 upvotes 5 months ago

Switching from finasteride to dutasteride can cause initial shedding, but many see long-term hair regrowth and stabilization. Responses vary, with some experiencing fewer side effects and others finding it less effective.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn Epidermal Growth Factor

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