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GlossaryAndrogen Receptor Gene Polymorphism

variations in the DNA sequence of the androgen receptor gene

Androgen Receptor Gene Polymorphism refers to variations in the DNA sequence of the androgen receptor (AR) gene, which can affect how the body responds to androgens, such as testosterone. These genetic differences can influence a range of physiological traits and conditions, including hair growth patterns and susceptibility to conditions like androgenetic alopecia (male or female pattern baldness).

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Research

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research Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne

186 citations , July 1998 in “Journal of Cutaneous Medicine and Surgery”

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Polymorphisms of the Androgen Receptor Gene and the Estrogen Receptor Beta Gene Are Associated with Androgen Levels in Women

research Polymorphisms of the Androgen Receptor Gene and the Estrogen Receptor β Gene Are Associated with Androgen Levels in Women1

93 citations , June 2001 in “The Journal of Clinical Endocrinology and Metabolism”

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

research Significance of the polyglutamine tract polymorphism in the androgen receptor

54 citations , November 2001 in “Urology”

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

research Androgen receptor gene polymorphism and polycystic ovary syndrome

45 citations , November 2012

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

research Androgen receptor gene CAG repeat polymorphism in women with polycystic ovary syndrome

44 citations , January 2008 in “Fertility and Sterility”

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

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community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community GT-20029 should be much more superior than finasteride

in Research/Science 44 upvotes 1 year ago

GT-20029 is discussed as a potential hair loss treatment, with concerns about its safety and systemic absorption compared to finasteride. Users express skepticism about its effectiveness and safety, noting that it may not surpass existing treatments like finasteride and minoxidil.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Maintaining hair until Breezula without Fin

in Treatment 6 upvotes 6 years ago

A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

community Creatine is the opposite of minoxidil !

in Research/Science 315 upvotes 9 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

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