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GlossaryAndrogen-Dependent

biological process influenced by male sex hormones

Androgen-dependent refers to biological processes or conditions that are influenced or regulated by androgens, which are male sex hormones like testosterone. For example, androgen-dependent hair loss, also known as androgenetic alopecia, occurs when hair follicles shrink due to the effects of these hormones, leading to thinning hair or baldness. This term is crucial in understanding conditions that are influenced by hormonal changes, particularly in the context of hair growth and loss.

Related Terms

Research

5 / 1000+ results

research Cultured dermal papilla cells from androgen-dependent human hair follicles (e.g. beard) contain more androgen receptors than those from non-balding areas of scalp

124 citations , April 1992 in “Journal of Endocrinology/Journal of endocrinology”

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

research Acquired Progressive Kinking of the Hair

26 citations , October 1999 in “Archives of Dermatology”

Curly hair in certain scalp areas can be an early sign of hair loss.

research Endocrinology Update: Hirsutism.

12 citations , December 2016 in “PubMed”

Hirsutism involves excessive hair growth due to hormonal issues and can be treated with medication or surgery.

research [Hirsutism and hypertrichosis in adults: investigations and treatment].

3 citations , May 2002 in “PubMed”

The document concludes that treatment for excessive hair growth depends on the cause, with options including hair removal methods and medications like anti-androgens or insulin-sensitizing drugs.

research Fibrosing alopecia in a pattern distribution after hair transplantation: A case report and literature review

May 2025 in “Journal of Clinical Images and Medical Case Reports”

Hair transplants can trigger a rare scarring hair loss that is hard to treat.

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Community Join

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community Topical Minoxidil 5% since March but does seem to be improving much.

in Progress Pictures 202 upvotes 11 months ago

Minoxidil 5% alone is not enough for significant hair regrowth; combining it with finasteride or dutasteride is advised. A hair transplant might be needed, depending on baldness extent and donor area quality.

community Target Area Hair Count (TAHC) increase comparasion of all future treatments in clinical trial phases

in Research/Science 35 upvotes 2 years ago

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

community If RU58841 is such an effective anti androgen

in Research/Science 46 upvotes 2 years ago

RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

community What if the prescribed amount of minoxidil doesn’t cover your whole “work” area?

in Minoxidil 10 upvotes 2 years ago

A user is concerned about using more minoxidil than prescribed to cover their hair loss area and mentions taking spironolactone pills. Another user advises against men taking oral spironolactone due to significant hormonal effects.

community Has anyone powered through the creatine shedding (via increased androgen receptor sensitivity) and stabilized?

in Update 8 upvotes 11 months ago

Creatine may cause increased hair shedding due to androgen receptor sensitivity, despite limited evidence. The user is using dutasteride and minoxidil and seeks advice on whether shedding will stabilize, with suggestions including GHK-Cu and RU58841.

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