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GlossaryAndrogen-Dependent Conditions

medical issues caused by male hormones like testosterone

Androgen-Dependent Conditions are medical issues that arise due to the effects of androgens, which are male hormones like testosterone. These conditions can affect both men and women and include problems like male pattern baldness (androgenetic alopecia), acne, and prostate enlargement. In these cases, the presence and activity of androgens play a crucial role in the development and progression of the condition.

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Research

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research ANDROGEN-DEPENDENT DERMOPATHY IN WOMEN WITH KELOID SCARS

January 2019 in “Paëmi Sino”

Women with keloid scars often have acne and hair loss, especially those with "true" keloids, indicating a possible hormonal imbalance.

research Three cases of androgen‐dependent disease associated with myotonic dystrophy

8 citations , January 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.

research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*

147 citations , April 1990 in “The Journal of Clinical Endocrinology and Metabolism”

Finasteride safely lowers DHT levels without affecting testosterone.

Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life

research Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life

19 citations , October 2017 in “The FASEB Journal”

Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.

research Nuclear and cytosol Androgen Receptor in Androgen Dependent Dermatoses in Female Patients

5 citations , July 2009 in “Experimental and Clinical Endocrinology & Diabetes”

Nuclear AR levels give better insight into hormone effects in skin conditions.

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community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 2 years ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

community Why I believe PFS is not a "real" condition (and what I believe it is instead)

in Finasteride/Dutasteride 14 upvotes 3 years ago

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

community If RU58841 is such an effective anti androgen

in Research/Science 46 upvotes 2 years ago

RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 64 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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