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GlossaryAndrogen-Related Conditions

health issues caused by male hormones like testosterone

Androgen-related conditions are health issues that arise due to the effects of androgens, which are male hormones like testosterone. These conditions can affect both men and women and include problems such as acne, hirsutism (excessive hair growth), and androgenic alopecia (pattern hair loss). In women, they can also be linked to polycystic ovary syndrome (PCOS), which can cause irregular menstrual cycles and fertility issues.

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research Balancing Hormones and Skin Health: A Focus on Oral Contraceptives in Dermatology

April 2025 in “La Prensa Medica”

Oral contraceptives help treat acne and hair issues by balancing hormones but need careful use due to possible side effects.

research Do clinical markers of hyperandrogenism relate to the response of acne to conventional therapy?

January 1990 in “Journal of dermatological treatment”

Clinical features of hyperandrogenism do not predict the success of conventional acne treatment in women.

research Hormonal Treatment for Skin Androgen-Related Disorders

January 2015

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

research Effect of the gonadotrophin releasing hormone analogue, goserelin, and oestradiol replacement on sebum excretion rates and hair size in mildly hirsute women

4 citations , January 1991 in “Journal of dermatological treatment”

Goserelin and oestradiol treatment slightly improved hairiness but did not significantly change sebum production or hair characteristics in mildly hirsute women.

research Three cases of androgen‐dependent disease associated with myotonic dystrophy

8 citations , January 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Women with myotonic dystrophy might get diseases related to male hormones because their body tissues are extra sensitive to these hormones.

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community Theoretically won't this be better than finasteride? Azelaic acid + zinc

in Research/Science 8 upvotes 3 years ago

The conversation discusses using zinc sulphate and azelaic acid to inhibit 5 alpha-reductase activity, which could potentially treat androgen-related skin conditions like hair loss. Combining these with vitamin B6 could enhance the effect, potentially offering an alternative to finasteride.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 2 years ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 4 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.