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Protective Role of Hesperidin in Finasteride-Induced Testicular Toxicity in Adult Male Wistar Rats: Insights Into Oxidative Stress, Apoptosis, and Ultrastructure of Seminiferous Tubules

research Protective role of hesperidin in finasteride-induced testicular toxicity in adult male Wistar rats: Insights into oxidative stress, apoptosis, and ultrastructure of seminiferous tubules

January 2024 in “Reproductive toxicology”

Hesperidin helps protect against testicular damage caused by finasteride.

research Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage

210 citations , May 2006 in “The FASEB journal”

Oxidative stress causes hair to gray by damaging and killing pigment cells.

Abstract P1-09-32: A Novel Candidate for Chemotherapy-Induced Alopecia Through Local Modulation of Apoptosis and Inflammation

research Abstract P1-09-32: A novel candidate for chemotherapy induced alopecia (CIA) through local modulation of apoptosis and inflammation

May 2015 in “Cancer Research”

A new treatment may prevent hair loss from chemotherapy by normalizing scalp cell death and reducing inflammation.

research Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen)

43 citations , December 2006 in “The American journal of pathology”

Edar signaling is crucial for controlling hair growth and regression.

Enhanced Viability and Neural Differentiation Potential in Poor Post-Thaw Human Adipose-Derived Stem Cells by Agarose Multi-Well Dishes and Spheroid Culture

research Enhanced viability and neural differential potential in poor post-thaw hADSCs by agarose multi-well dishes and spheroid culture

15 citations , June 2015 in “Human Cell”

Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 3 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Possible transgenerational effects of finasteride use on male offspring? (STUDY)

in Research/Science 27 upvotes 3 months ago

Finasteride may affect male offspring's fertility and hormonal balance, with debates on whether to discontinue use before conception. Some users report no issues, while others highlight the high doses used in rat studies.

community I hope ET-02 or PP405 will be released in the next 4-5 years

in Product 15 upvotes 1 year ago

PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

community Anti-oxidants that reverse hairloss?

in Research/Science 90 upvotes 5 years ago

Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.

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