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GlossaryBenzimidazole

organic compound with antifungal and antiparasitic properties

Benzimidazole is a type of organic compound that consists of a fusion between benzene and imidazole rings. It is commonly used in pharmaceuticals for its antifungal and antiparasitic properties, making it effective in treating infections and certain types of worms. Additionally, benzimidazole derivatives are being researched for their potential in cancer treatment and other medical applications.

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Research

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research Medical Treatment of Liver Hydatidosis

126 citations , January 2001 in “World Journal of Surgery”

Surgery is the main treatment for liver hydatidosis, but has risks; albendazole is the most effective drug but can have side effects.

research Screening of drugs with potential antifungal activity for repurposing in the treatment of cryptococcosis.

March 2025 in “PubMed”

Certain antiparasitics and antidepressants show promise for treating cryptococcosis, especially when combined with fluconazole.

research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1

28 citations , September 2000 in “Journal of Medicinal Chemistry”

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

research Bicalutamide

January 2025

research Anthelmintic effect of Mentha spp. essential oils on Echinococcus granulosus protoscoleces and metacestodes

66 citations , August 2011 in “Parasitology Research”

Mint essential oils can kill parasites that cause cystic echinococcosis, with M. pulegium oil being more effective than M. piperita oil.

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Community Join

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community Pyrilutamide vs enzalutamide. Same thing?( Especially for biochemists, farmacologists)

in Research/Science 17 upvotes 3 years ago

Researching whether pyri and enza, which are stereoisomers of each other, share the same features related to CNS penetration/GABA Inhibition; safety and efficacy when used topically at 0.5-1%; and cost comparison between the two treatments.

community Pyrludimide (KX-826) or Breezula (clascoterone)

in Treatment 9 upvotes 3 weeks ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community Pyrilutamide Phase 3 on its way

in Treatment 129 upvotes 4 years ago

Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

community Anyone have any experience with “tiniazol” ketoconazole shampoo.

in Ketoconazole 3 upvotes 4 years ago

The conversation is about using ketoconazole shampoo for hair loss, specifically discussing concerns about benzyl alcohol in popular brands and seeking experiences with the "tiniazol" brand. The user is considering adding this shampoo to their routine.

community I'm very skeptical about pyrilutamide

in Product 2 upvotes 2 months ago

Pyrilutamide's effectiveness is questioned due to overstated claims and previous trial ineffectiveness, with some users opting for finasteride instead. Despite skepticism, some consider adding pyrilutamide to their regimen alongside treatments like bicalutamide.

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