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GlossaryBone Healing

process where broken bones naturally repair and regenerate

Bone healing, also known as bone regeneration or fracture healing, is the process by which a bone repairs itself after a fracture. This complex biological process involves several stages: inflammation, soft callus formation, hard callus formation, and bone remodeling. During these stages, the body produces new bone tissue to bridge the gap created by the fracture, eventually restoring the bone's original structure and strength.

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Research

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Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes

research Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes

160 citations , January 2017 in “Development”

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Transplantation of Bone-Marrow-Derived Mesenchymal and Epidermal Stem Cells Contribute to Wound Healing with Different Regenerative Features

research Transplantation of bone-marrow-derived mesenchymal and epidermal stem cells contribute to wound healing with different regenerative features

36 citations , April 2013 in “Cell and Tissue Research”

Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.

Combinatorial Influence of Bone Marrow Aspirate Concentrate and Platelet-Rich Plasma Treatment on Cutaneous Wound Healing in BALB/c Mice

research Combinatorial Influence of Bone Marrow Aspirate Concentrate (BMAC) and Platelet-Rich Plasma (PRP) Treatment on Cutaneous Wound Healing in BALB/c Mice

June 2023 in “Journal of Burn Care & Research”

Using both bone marrow concentrate and platelet-rich plasma together improves skin wound healing in mice.

research Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

139 citations , May 2020 in “Stem Cell Research & Therapy”

Exosomes from stem cells help wounds heal faster by affecting specific cell signals.

research Human bone marrow mesenchymal stem cells-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

1 citations , May 2020 in “Research Square (Research Square)”

Exosomes from stem cells help wounds heal faster by affecting specific cell signals.

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Community Join

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community Heating foam minoxidil into a liquid?

in Minoxidil 18 upvotes 6 years ago

Heating foam minoxidil into a liquid for easier application and quicker drying. Effectiveness remains the same as liquid minoxidil.

community Creatine and hair loss...you're not crazy.

in Research/Science 6 upvotes 6 months ago

Creatine may increase DHT levels, potentially causing hair loss in some people, though experiences vary. Treatments like finasteride or minoxidil are suggested to manage potential hair loss.

community Diffuse thinning fucking sucks

in Update 430 upvotes 2 years ago

The conversation discusses various treatments for hair loss, including finasteride, minoxidil, dutasteride, microneedling, and checking for nutrient deficiencies. Some users suggest adding hydrocortisone butyrate, low-dose progesterone, or tretinoin to treatment regimens, while others recommend cosmetic solutions like Toppik hair fibers or shaving the head.

community Lost 65% of hair last 3 years. No regrowth. Also have Seborrheic Dermatitis flare ups. Diagnosed by derm as "alopecia". Started taking 2 supplements I researched and 0 flare up for over 2 months. New hair growing. Scalp healthy. Everything else has stayed the same! Overjoyed is an understatement!!

in Treatment 18 upvotes 3 years ago

After suffering from hair loss and Seborrheic Dermatitis for three years with no improvement from various treatments, the individual found success with COQ10 and PQQ supplements, which led to new hair growth and a healthy scalp without flare-ups. They also plan to start additional supplements recommended by a dermatologist.

community One year on finasteride has reversed some aging

in Chat 198 upvotes 10 months ago

Finasteride and minoxidil use resulted in a more youthful appearance and improved skin. There is debate about their effects on collagen and skin aging, with no solid evidence supporting significant changes due to finasteride.

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