June 2024 in “Dermatology and therapy” Intramuscular injections improved hair density more than intradermal injections for treating hair loss.
53 citations
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January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
52 citations
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January 2023 in “Toxins” Botulinum toxin can safely and effectively treat facial wrinkles and muscle issues with precise injection techniques.
8 citations
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March 2020 in “Pain Medicine” This case report described a 25-year-old female with refractory trichodynia, a condition characterized by scalp pain and discomfort, potentially linked to hair loss. Traditional treatments, including pregabalin, amitriptyline, and propranolol, were ineffective. The patient was treated with off-label onabotulinumtoxin-A (BoNT-A) injections, which led to significant improvement and eventual resolution of symptoms after three treatment cycles over nine months. The study suggested that BoNT-A could modulate pain by inhibiting neuropeptide release, offering a potential new treatment for trichodynia, especially in cases unresponsive to conventional therapies. Further research was recommended to explore BoNT-A's efficacy in larger patient populations and its potential impact on hair loss associated with trichodynia.
5 citations
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May 2022 in “Molecules” Botulinum toxin is effective for various skin conditions, but more research and awareness of side effects are needed.