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research The brain–gut–skin axis in inflammatory and disfiguring skin diseases: mechanistic insights, clinical correlations, and therapeutic strategies

February 2026 in “Frontiers in Immunology”

Skin diseases like acne and psoriasis are linked to stress, gut health, and inflammation, with new treatments focusing on gut and mind-body approaches.

research Gut microbes and skin disease, gut-brain-skin axis: A review

3 citations , January 2017 in “Chinese Science Bulletin (Chinese Version)”

Balancing gut microbes and managing stress can help improve skin conditions like eczema and acne.

research The Gut-Brain-Skin Axis and Role of Intestinal Dysbiosis in Acne Vulgaris: Therapeutic Effects of Pro- and Prebiotic Use

2 citations , January 2018 in “Elsevier eBooks”

Probiotics and dietary changes can help treat acne.

research Is there a ‘gut–brain–skin axis’?

185 citations , January 2010 in “Experimental Dermatology”

Probiotics may help reduce stress-related skin issues and improve hair growth.

research Revisiting Rosacea Through the Skin–Gut–Brain Axis: A Neuroimmune Perspective

February 2026 in “Life”

Rosacea may be linked to gut and brain issues, not just a skin problem.

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community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 2 years ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community A hill on which I will die: The DHT itch absolutely exists

in Research/Science 210 upvotes 2 years ago

The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

community Finally Scalp Folliculitis-Free after 2 Decades of Suffering

in Treatment 62 upvotes 1 year ago

A 37-year-old male resolved scalp folliculitis by adopting a low-histamine diet and taking Vitamin A, Zinc, and Fish Oil, leading to better skin health and thicker hair. He warns about the potential toxicity of excessive Vitamin A intake.

community Derma told me to quit finastirde

in Finasteride/Dutasteride 276 upvotes 9 months ago

A dermatologist advised stopping finasteride after 3-6 months, but many users disagreed, stating it should be used indefinitely to maintain hair. Users recommended finding a new dermatologist due to the perceived misinformation.

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