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GlossaryBrain-Derived Neurotrophic Factor

protein supporting neuron growth and survival in the brain

Brain-Derived Neurotrophic Factor (BDNF) is a protein that plays a crucial role in the growth, maintenance, and survival of neurons in the brain. It is essential for cognitive functions such as learning and memory, and it also supports the health of existing neurons while encouraging the growth of new ones.

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Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor Beta 2 Expression

research Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor β2 Expression

64 citations , March 2005 in “Journal of Investigative Dermatology”

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

research Histone deacetylase inhibitors promote neurosteroid‐mediated cell differentiation and enhance serotonin‐stimulated brain‐derived neurotrophic factor gene expression in rat C6 glioma cells

35 citations , April 2009 in “Journal of Neuroscience Research”

HDAC inhibitors help brain cells grow and improve brain function.

research Reduced serum brain-derived neurotrophic factor in patients with first onset vitiligo

9 citations , December 2014 in “Neuropsychiatric Disease and Treatment”

People with first-time vitiligo have lower levels of a certain brain protein compared to healthy individuals.

research Serum brain‐derived neurotrophic factor and vitamin D: Two concordant players controlling depression among alopecia areata and vitiligo patients: A case–control study

6 citations , March 2023 in “Journal of Cosmetic Dermatology”

Low levels of BDNF and vitamin D are linked to higher depression in alopecia areata and vitiligo patients.

research Evaluation of serum brain-derived neurotrophic factor to assess the association between psoriasis and depression

2 citations , September 2015 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

People with psoriasis and depression have lower BDNF levels, which could help measure depression in those with psoriasis.

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community Possible topical option for preventing BDNF-related hair loss

in Research/Science 8 upvotes 2 years ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

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