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GlossaryCancer

uncontrolled growth and spread of abnormal cells

Cancer, also known as a malignant tumor or malignant neoplasm, is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. If the spread is not controlled, it can result in death. Cancer can develop in almost any part of the body and often forms a mass called a tumor, although not all cancers form tumors (e.g., leukemia). The study and treatment of cancer fall under the field of oncology.

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Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

402 citations , August 2011 in “Cancer research”

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

research Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer: a single‐arm phase II study

147 citations , October 2021 in “Cancer Communications”

RC48 shows promise for treating certain advanced cancers, but more research is needed.

research Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells

145 citations , May 2008 in “Cancer Science”

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

research Normal stem cells and cancer stem cells: similar and different

126 citations , April 2010 in “Seminars in Cancer Biology”

Deregulation of stem cell function is central to the development of some cancers.

research Stretching the limits: from homeostasis to stem cell plasticity in wound healing and cancer

124 citations , February 2018 in “Nature Reviews Genetics”

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

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community Cancer took my hair 3 times. Trying to get it back!

in Journals / Progress Pictures 269 upvotes 1 year ago

OP is using 5% minoxidil and a needler to regrow hair after chemotherapy-induced hair loss. Another user mentions using finasteride and topical minoxidil, noting some improvement in hair density.

community Anyone had a Hair transplant after cancer?

in Hair Transplants 98 upvotes 1 year ago

A blood cancer survivor in remission since 2022 is experiencing thin and patchy hair after chemotherapy and is using Minoxidil without much success. They are seeking personal experiences and advice on hair transplants after cancer treatment.

community Does RU58841 potentially cause cancer?

in Research/Science 1 year ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

community Does drinking topical minoxidil increase cancer risk?

in Minoxidil 11 months ago

A user has been using sublingual minoxidil for hair loss due to difficulty obtaining pills and is concerned about cancer risk from ethanol exposure. Other users advise against this method, suggesting topical application instead, and debate the potential risks of ingesting topical minoxidil.

community Is There Any Chance Of Cancer In Follicle Neogenesis through Microneedling?

in Microneedling 15 upvotes 6 years ago

The conversation discusses concerns about the potential risk of cancer from creating new hair follicles through microneedling, due to stem cell division. Specific treatments mentioned include microneedling, caffeine-containing anti-hair loss shampoos, and other unspecified topicals.

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