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GlossaryCandidate Genes

specific genes believed to influence a particular trait or disease

Candidate genes are specific genes that researchers believe may be associated with a particular trait or disease, based on their known biological functions or previous studies. For example, in the context of alopecia (hair loss), scientists might identify candidate genes that are involved in hair growth or immune system regulation, as these processes are relevant to the condition. Identifying and studying these genes can help in understanding the underlying mechanisms of the disease and potentially lead to targeted treatments.

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Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia

research Differential Expression between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia

46 citations , April 2016 in “Journal of Investigative Dermatology”

New genes found linked to balding, may help develop future treatments.

research Candidate genes of SARS-CoV-2 gender susceptibility

27 citations , November 2021 in “Scientific Reports”

Men are more affected by COVID-19 due to differences in immune responses and protein expression.

research Candidate Gene Analysis Of Alopecia Areata In Jordanian Population Of Arab Descent: A Case–Control Study

6 citations , November 2019 in “The application of clinical genetics”

The study found that a specific genetic variation in the TNFα gene is significantly linked to Alopecia Areata in the Jordanian Arab population.

research Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes

3 citations , February 2025 in “Journal of PHYSIOLOGICAL ANTHROPOLOGY”

Certain genes are linked to skin aging, like wrinkles and pigmentation changes.

Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters

research Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters

16 citations , February 2018 in “BMC Genomics”

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

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Community Join

5 / 436 results

community Am I a good candidate for finasteride? (Bloodwork) 18M NW2

in General 56 upvotes 1 year ago

An 18-year-old with Norwood 2 hair loss is considering finasteride treatment. Bloodwork shows testosterone and hormone levels mostly within normal ranges, except for low estradiol.

community Should i shave it? Need some help, general advice

in General 149 upvotes 1 year ago

A 27-year-old male has been using finasteride for six years and recently started oral minoxidil to address hair loss, experiencing some side effects like lightheadedness. He is considering shaving his head or a hair transplant while continuing his current treatments.