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GlossaryCapsaicin

active compound in chili peppers causing heat sensation

Capsaicin is the active component in chili peppers that gives them their characteristic heat. It works by binding to pain receptors in the mouth and skin, which can cause a burning sensation. Interestingly, capsaicin is also used in topical creams to relieve pain by desensitizing sensory neurons, and some studies suggest it may promote hair growth by increasing blood flow to the scalp.

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research Brachioradial Pruritus: Treatment with Topical Capsaicin

56 citations , November 1993 in “Journal of The American Academy of Dermatology”

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

research Efficacy of a Mixed Preparation Containing Piperine, Capsaicin, and Curcumin in the Treatment of Alopecia Areata

4 citations , March 2022 in “Journal of cosmetic dermatology”

The mixed preparation helped hair regrowth but wasn't better than minoxidil.

research The Effect of Coapplication of Capsaicin and Minoxidil on Murine Hair Growth

April 2003 in “Journal of Clinical Dermatology”

Capsaicin and minoxidil together lead to quick, steady hair growth.

research A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control

174 citations , April 2005 in “The American journal of pathology (Print)”

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

research A Hair Growth-Promoting Effect of Chinese Black Tea Extract in Mice

3 citations , July 2013 in “Bioscience, Biotechnology, and Biochemistry”

Chinese black tea extract helped mice grow hair, especially when combined with capsaicin.

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community Growing hair witch capsaicin and occasional topical minoxidil

in Progress Pictures 59 upvotes 5 days ago

A user shared their experience using capsaicin from chili peppers and occasional topical minoxidil to promote hair growth, noting noticeable improvements without significant side effects. They previously experienced side effects from dutasteride and minoxidil but found the new regimen effective and manageable.

community Soy Isoflavones and Capsaicin for Hair Growth

7 upvotes 14 years ago

The conversation discusses using soy isoflavones and capsaicin for hair growth. It also mentions treatments like Minoxidil, finasteride, and RU58841.

community Natural methods only. Gains or Nah?

in Is this regrowth? 2 months ago

The user is attempting to regrow hair using natural methods like microneedling, rosemary oil, and capsaicin tincture, avoiding medications like finasteride and minoxidil due to past health issues. Feedback suggests these methods are ineffective, with many recommending shaving or considering a hair system instead.

community Possible topical option for preventing BDNF-related hair loss

in Research/Science 6 upvotes 2 years ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community New molecule PP405 vs exercise

in Research/Science 38 upvotes 9 months ago

PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

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