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research Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt

83 citations , October 2012 in “International Journal of Oncology”

Wedelolactone selectively kills prostate cancer cells without harming normal cells.

research Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size

90 citations , May 2018 in “Molecular Cell”

Caspase-3 helps control cell growth and organ size by activating YAP.

research Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia

28 citations , December 2001 in “European Journal of Pharmacology”

M50054 may help treat hepatitis and hair loss from chemotherapy.

research Inhibition of CCAAT/Enhancer Binding Protein Family DNA Binding in Mouse Epidermis Prevents and Regresses Papillomas

28 citations , February 2007 in “Cancer Research”

Blocking certain proteins in mouse skin can reduce and shrink skin tumors.

research Integrin-linked kinase inhibition via QLT0267 stops the epithelial outgrowth.

December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)”

QLT0267 stops hair follicle cell growth and movement.

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community Don't use PP405 from everychem. it is likely fake.

in Research/Science 67 upvotes 1 year ago

PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

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