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GlossaryCD200 receptor

protein on immune cells that regulates immune response

The CD200 receptor (CD200R) is a protein found on the surface of certain immune cells, such as macrophages and dendritic cells. It plays a crucial role in regulating the immune response by interacting with its ligand, CD200, to send inhibitory signals that help prevent excessive inflammation and autoimmunity. This interaction is important in maintaining immune tolerance and has implications in conditions like alopecia, where immune regulation is disrupted.

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research 24 ARQ-234: a high affinity CD200-Fc fusion protein for the treatment of atopic dermatitis

November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

ARQ-234, a protein designed to treat atopic dermatitis, shows increased effectiveness in early testing.

research Canine and Feline Cutaneous Lymphocytosis: Reactive Process or Indolent Neoplastic Disease?

1 citations , December 2021

Cats likely have a reactive skin condition, while dogs may have a more complex, possibly cancerous one.

research A helminth mimic of TGF-β, TGM, enhances regenerative cutaneous wound healing and modulates immune cell recruitment and activation

September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

A parasite-derived molecule speeds up skin healing and affects immune cell behavior without increasing scarring.

The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

research The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

32 citations , January 2012 in “Clinical & Developmental Immunology”

Targeting CD200 could be a new treatment for rheumatoid arthritis.

research A case of recurrent acute pancreatitis following ocrelizumab use

April 2024 in “DAHUDER Medical journal”

Ocrelizumab may cause pancreatitis in some patients.

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community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

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