Search

for
Search:

GlossaryCD73

enzyme converting extracellular AMP to adenosine, impacting inflammation

CD73, also known as ecto-5'-nucleotidase, is an enzyme found on the surface of many cell types. It plays a crucial role in the immune system by converting extracellular AMP (adenosine monophosphate) into adenosine, which has anti-inflammatory effects. This enzyme is significant in various physiological processes, including tissue protection and repair, and is being studied for its potential role in cancer and autoimmune diseases.

Related Terms

Research

5 / 287 results

research 217 The adenosine-generating ecto-enzyme CD73 regulates human hair growth

August 2016 in “Journal of Investigative Dermatology”

The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.

research 671 The adenosine-generating ecto-enzyme, CD73, functions as an intrafollicular regulator of human hair growth

April 2016 in “Journal of Investigative Dermatology”

CD73 may regulate hair growth and could be targeted for hair growth treatments.

research Tregs: Where We Are and What Comes Next?

130 citations , November 2017 in “Frontiers in Immunology”

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.