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GlossaryCell Adhesion

process where cells stick to each other or surfaces

Cell adhesion refers to the process by which cells interact and attach to neighboring cells or the extracellular matrix through specialized protein structures on their surfaces. This interaction is crucial for maintaining the structural integrity of tissues, facilitating communication between cells, and playing a key role in processes like wound healing and immune responses.

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Research

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research 644 Tumor cell adhesion as a risk factor for SLN metastasis and predictor of disease recurrence in primary cutaneous melanoma

April 2016 in “Journal of Investigative Dermatology”

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion

research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion

72 citations , November 2012 in “PloS one”

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

RSPO1-Mutated Keratinocytes From Palmoplantar Keratoderma Display Impaired Differentiation and Invasiveness: Implications for Squamous Cell Carcinoma Susceptibility in Patients With 46XX Disorder of Sexual Development

research RSPO1-mutated keratinocytes from palmoplantar keratoderma display impaired differentiation, alteration of cell–cell adhesion, EMT-like phenotype and invasiveness properties: implications for squamous cell carcinoma susceptibility in patients with 46XX disorder of sexual development

5 citations , July 2022 in “Orphanet journal of rare diseases”

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

research Dynamic expression patterns of tenascin, proteoglycans, and cell adhesion molecules during human hair follicle morphogenesis

67 citations , February 1994 in “Developmental dynamics”

Specific proteins and molecules play key roles in the development of human hair follicles.

research Protective effects of finasteride against testosterone-induced calcium oxalate crystallization and crystal-cell adhesion

15 citations , July 2019 in “Journal of Biological Inorganic Chemistry”

Finasteride helps prevent kidney stones, but side effects need more research.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Apple stem cell

learn Stem Cell Factor

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community The Real Cause Of Androgenetic Alopecia

in Research/Science 677 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Any experience with stem cell hair transplants?

in Transplants 25 upvotes 3 years ago

Stem cell hair transplants use stem cells from fat tissue to reactivate inactive hair follicles, but results are inconsistent and not widely shared. Traditional treatments like finasteride and minoxidil often show better results.

community Has anyone here actually undergone experimental (grey market) hair cell therapy/follicle cloning?

in Technology 6 upvotes 3 months ago

Hair cell therapy and follicle cloning are still in experimental stages, with treatments like hair multiplication and regenerative hair therapy being marketed but not yet proven to create unlimited new follicles. There is skepticism about the effectiveness and legitimacy of these treatments, with some considering them scams.

community What do you guys think of stem cell hai restoration?

in Chat 9 upvotes 7 months ago

Stem cell hair restoration lacks scientific evidence and is often considered a scam. Effective hair loss treatments include hair transplants, Minoxidil, and Finasteride, but stem cell treatments are not proven.

community PRP + Stem Cell Treatment For Hairloss

in Treatment 4 upvotes 11 months ago

A user shared their positive experience with PRP and stem cell treatment for hair loss, noting it nearly stopped their hair loss after previous use of finasteride and minoxidil. Another user mentioned PRP helped maintain their hair, though its effectiveness decreased over time, and they experienced side effects from dutasteride.

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