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GlossaryCentral Centrifugal Cicatricial Alopecia

scarring hair loss starting at the scalp's crown, common in African American women

Central Centrifugal Cicatricial Alopecia (CCCA) is a type of scarring hair loss that typically starts at the crown of the scalp and spreads outward in a circular pattern. It is most commonly seen in African American women and can lead to permanent hair loss due to the destruction of hair follicles and subsequent scarring.

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Characteristics of Central Cicatricial Centrifugal Alopecia in Elderly vs. Younger Patients

research Characteristics of central cicatricial centrifugal alopecia that developed in elderly compared with younger patients

September 2018 in “Journal of the American Academy of Dermatology”

Elderly patients with CCCA were all African American with low vitamin D, but no iron or zinc deficiencies, and no hormonal imbalances compared to younger patients.

research Central centrifugal cicatricial alopecia – an approach to diagnosis and management

32 citations , November 2011 in “International Journal of Dermatology”

Diagnose and manage CCCA with thorough history, exams, and labs; treat with anti-inflammatory agents, stress reduction, and stopping harmful hair practices.

research Central centrifugal cicatricial alopecia: possible familial aetiology in two African families from South Africa

15 citations , November 2012 in “International Journal of Dermatology”

The conclusion is that hair loss from CCCA may be genetic and not solely caused by hair grooming practices.

research Central centrifugal cicatricial alopecia: Past, present, and future

75 citations , March 2009 in “Journal of The American Academy of Dermatology”

CCCA is a hair loss type affecting African women, possibly caused by grooming and chemicals, with various treatments and needing more research.

research Central Centrifugal Cicatricial Alopecia: New Insights and a Call for Action

27 citations , September 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

Hair loss in black women needs more research, early intervention, and community education.

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community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Wanted to say that Derma rolling and Pumpkin seed oil helped my crown out.

in Treatment 4 upvotes 6 years ago

Derma rolling, pumpkin seed oil, and daily massages helped regrow weak hairs on the crown. Nizoral shampoo and yoga also contributed to reducing scalp pain and stress.

community Finasteride doesn't work for me in 2 years and my bloodtest result just came in.

in Progress Pictures 88 upvotes 2 years ago

A user has been treating hair loss with finasteride for two years without success and is experiencing an itchy scalp with seborrhea. Despite low DHT levels, they are still losing hair, suggesting that DHT might not be the main cause of their hair loss, and they are considering other treatments or causes.

community lost my hair in a single year of treatment at 20 years old

in Finasteride/Dutasteride 90 upvotes 2 years ago

A 20-year-old lost significant hair after one year of treatment, using minoxidil, finasteride, and later dutasteride. They are considering adding RU58841 but are advised to return to finasteride and minoxidil for a year before deciding.

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