research DNA Damage, Checkpoint Responses, and Cell Cycle Control in Aging Stem Cells
Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
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research Replicative Stress, Stem Cells, and Aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research A Mouse Model of Vitiligo Based on Endogenous Auto-Reactive CD8+ T Cell Targeting Skin Melanocyte
A new mouse model effectively mimics vitiligo for research and drug testing.
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5 / 6 resultscommunity Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.
Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.
community PP405 - A True Breakthrough or Another Disappointment?
PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.
community Oral min 2.5mg / oral fin 1mg / 3.5 months - 25M progress
A 25-year-old shared progress on hair growth using oral minoxidil 2.5mg, oral finasteride 1mg, and dermarolling over 3.5 months, noting improvements and encouraging others to persist with treatments. Other users discussed their experiences with similar treatments, including topical minoxidil, ketoconazole shampoo, and tretinoin cream, with varying results and side effects.
community Dutasteride Infertility Debunked: Low T causes true infertility.
Dutasteride and finasteride may temporarily affect semen quality but are unlikely to cause permanent infertility. The Kim et al. study is criticized for poor methodology, and many prefer hair retention over potential fertility concerns, using treatments like dutasteride, finasteride, and minoxidil.
community 6th Month Checkpoint! There is progress (I think?)
The conversation discusses a user's six-month progress in treating hereditary hair loss using a regimen that includes minoxidil, finasteride, dutasteride, and other medications. Opinions vary on the effectiveness and logic of the treatment, with some users suggesting additional methods like microneedling.