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Did you mean Chronic Graft-Versus-Host Disease?

GlossaryChronic Graft-Versus-Host Disease

condition where transplanted cells attack recipient's body long-term

Chronic Graft-Versus-Host Disease (cGVHD) is a condition that can occur after a stem cell or bone marrow transplant, where the donated cells (the graft) attack the recipient's body (the host). This immune response can lead to long-term complications affecting various organs, including the skin, liver, and gastrointestinal tract, and can manifest as rashes, liver dysfunction, and digestive issues.

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Risk Factors and Characterization of Vitiligo and Alopecia Areata in Patients With Chronic Graft-Versus-Host Disease

research Risk Factors and Characterization of Vitiligo and Alopecia Areata in Patients With Chronic Graft-vs-Host Disease

27 citations , September 2014 in “JAMA dermatology”

Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

High Frequency of Cutaneous Manifestations Including Vitiligo and Alopecia Areata in a Prospective Cohort of Patients with Chronic Graft-Versus-Host Disease

research High frequency of cutaneous manifestations including vitiligo and alopecia areata in a prospective cohort of patients with chronic graft-vs-host disease

17 citations , June 2016 in “Croatian Medical Journal”

Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.

research Alopecia Universalis and Chronic Graft-vs-Host Disease Treated With Ruxolitinib

4 citations , October 2018 in “JAMA Dermatology”

Ruxolitinib may help treat hair loss and symptoms in patients with chronic graft-versus-host disease.

Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome

research Rapid full engraftment and successful immune reconstitution after allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in Omenn syndrome

8 citations , August 2009 in “Pediatric transplantation”

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

Towards a Consensus Potency Assay for Mesenchymal Stromal Cells: A Matrix Analysis of Cell Source, Donor Variability, and Inflammatory Stimuli to Refine Surrogate Markers of Immunomodulation

research Towards a consensus potency assay for mesenchymal stromal cells: a matrix analysis of cell source, donor variability and inflammatory stimuli to refine surrogate markers of immunomodulation

3 citations , May 2019 in “Cytotherapy”

ATIR101 improves survival in stem cell transplant patients; Australian stem cell treatment decisions are influenced by regulation changes.

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community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 1 year ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 94 upvotes 6 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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