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    GlossaryCancer-Associated Fibroblasts

    specialized cells in tumors that support cancer growth and spread

    Cancer-Associated Fibroblasts (CAFs) are specialized cells found within the tumor microenvironment that play a crucial role in cancer progression. They support tumor growth by remodeling the extracellular matrix, promoting angiogenesis (formation of new blood vessels), and secreting signaling molecules that enhance cancer cell survival and invasion.

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