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GlossarySAPHO syndrome

rare disorder causing joint inflammation and severe skin conditions

SAPHO syndrome is a rare, chronic disorder that stands for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis. It primarily affects the skin and bones, leading to painful inflammation in the joints and skin conditions like severe acne and pustules. The exact cause is unknown, but it is believed to involve both genetic and environmental factors.