Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.
A pharmacy error resulted in a finasteride solution being 100 times stronger than prescribed, not 10,000 times as initially feared. OP is advised to contact the pharmacy to clarify the preparation before traveling.
A user in Russia is trying to make topical finasteride at home using ethanol, finasteride tablets, water, and propylene glycol due to unavailability in their country. They are concerned about tablet residue and considering using isopropyl alcohol or adding finasteride to a hair growth lotion.
A user shares their positive experience using the Rootique Dou applicator with 0.005% finasteride, noting it effectively delivers the product without greasiness and helps with hair regrowth without side effects. Another user reports regrowth using low-dose finasteride from ULO, while avoiding tretinoin due to skin irritation.
A 24-year-old shared six months of progress using 1mg finasteride daily and topical minoxidil twice daily, reporting improved hairline and temples with no side effects. The user experienced initial shedding but noted significant regrowth and no erectile dysfunction issues.
The conversation discusses dosing for 1000mg Pumpkin Seed Oil tablets and compares its DHT-lowering effects to finasteride. The user considers splitting the tablets to achieve a 500mg dose.
The conversation is about the effectiveness of a hair loss treatment product containing 0.01% Latanoprost, with the user considering trying it as a vehicle for RU58841. The user questions whether the dosage is too low to be effective.
PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.
Oleic acid and ethanol are being considered for hair regrowth, with some users planning to self-experiment. There is skepticism about their effectiveness, and ongoing use of treatments like finasteride and minoxidil is mentioned.
The user saw hair regrowth after inconsistently using treatments like microneedling, peppermint and rosemary oils, ketoconazole shampoo, zinc pyrithione shampoo, and scalp massages, but stopped minoxidil due to heart palpitations. They plan to start a consistent treatment with a minoxidil and finasteride topical solution and will share results in six months.
Pregnancy can temporarily reverse hair loss in women, but attempts to mimic pregnancy hormones with treatments like contraceptive pills, spironolactone, estradiol, progesterone, finasteride, and minoxidil have been ineffective. The discussion highlights the need for research into the hormonal mechanisms of pregnancy that affect hair regrowth.
IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.
A user reported a significant reduction in DHT levels after 3 months of taking 1mg/day oral finasteride, along with using minoxidil foam, microneedling, and Nutrafol vitamins. They hope this will lead to hair growth and less shedding.
The conversation discusses the fluctuation of testosterone levels in men under 40 and the difference between serum DHT and scalp DHT. It also mentions that DHT levels are higher on Dutasteride than on Finasteride, which is unusual.
The user has been taking 0.25mg of oral finasteride daily for a month and is considering increasing the dose to 1/3 of a pill. They have also been using topical minoxidil for several years.
The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.
The user is using a combination of finasteride, dutasteride, oral and topical minoxidil, PRP, and stem cell treatments for hair loss. They report slowed shedding and new vellus hairs on the hairline, questioning if they are a strong responder to the treatment.
A user experienced mild side effects from 0.5mg finasteride daily, including increased estradiol and minor gynecomastia. They are considering taking a low dose of exemestane to reduce estrogen levels.
Clascoterone has shown promising results in increasing hair density without systemic side effects, potentially offering benefits similar to finasteride. There is skepticism due to the lack of published photos despite the market interest.
A 49-year-old is sharing progress on hair regrowth using PRP sessions and a combination of treatments, including minoxidil, but not oral finasteride or dutasteride. Users suggest adding oral treatments like dutasteride or minoxidil for better results.
A user discovered they have naturally low DHT levels and is concerned about taking finasteride, which could further lower these levels. They are seeking advice on whether to proceed with the treatment given their hormone levels are within the normal range.
The user shared progress pictures showing hair growth after using finasteride 1mg and minoxidil 5% daily for three years. Commenters are impressed, discussing the effectiveness and asking about additional treatments like derma rolling and side effects.
The user shared their hormone levels over time while using finasteride and dutasteride for hair loss. They experienced a significant drop in DHT levels but continued to lose hair, hoping for better results in the future.
PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.
The potential hair regrowth benefits of ASC-J9, a synthetic modified version of curcumin that is said to be more effective than Minoxidil and Finasteride. Reports from users suggest good thickening and temple regrowth with topical use at 0.025% concentration.
A user shares their 11-week progress using 1mg finasteride, 5% minoxidil twice daily, 0.8mm dermastamping every 10 days, occasional tretinoin, and ketoconazole shampoo for hair regrowth. They plan to continue the treatment for 9 months before considering a hair transplant.
A 24-year-old is experiencing hair shedding and regrowth while using dutasteride (1mg), vitamin D, and minoxidil (5%). Others share similar experiences with hair loss treatments like minoxidil and finasteride.
A 23-year-old man shared his one-year progress using finasteride for hair loss, starting with a lower dose due to side effects and gradually increasing to 1mg. He experienced manageable side effects and is considering adding minoxidil or switching to dutasteride in the future.