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      community Caffeine & Alopecia: What the Science Seems to Say

      in Research/Science  16 upvotes 2 years ago
      The conversation discusses the potential benefits of topical caffeine for Androgenetic Alopecia (APA) and female pattern hair loss. While some studies suggest positive results, there's no reliable scientific evidence to strongly recommend caffeine compounds for hair regrowth.

      community Is there new research about pumpkin oil as a DHT blocker (2026)?

      in Research/Science  9 upvotes 1 week ago
      Pumpkin seed oil is considered a weak DHT blocker compared to finasteride and dutasteride, with some users reporting side effects like mood changes and reduced libido. Despite some anecdotal benefits for urinary issues, it is not effective for hair loss, and finasteride is preferred by some users for its lack of side effects.

      community I had claude create a protocol only using fda approved drugs.

      in Research/Science  3 upvotes 4 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community Summary of Procapil video by Haircafe

      in Minoxidil  2 upvotes 9 months ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

      community Everyone seems to be looking for an antiandrogen as an add on. But what about Estradiol & its derivatives ( excluding the low concentraion alfatradiool ) being used. Anyone has an experience with this ? Anything that won't cause feminization in the process ?

      in Chat  5 upvotes 1 year ago
      The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).

      community Year and 3 months progress (28m) fin + min

      in Progress Pictures  328 upvotes 1 year ago
      A user shared their 15-month hair regrowth progress using 1mg finasteride daily and topical minoxidil once daily, noting significant improvement after adding finasteride. They experienced mild side effects, including reduced erection strength after a year.

      community Anyone here going the “natural” route?

      in Scalp Massage  48 upvotes 3 years ago
      People discussing their experiences with natural treatments for hair loss, such as essential oils, deep scalp massages, anti-inflammatory measures, and supplements. Most of the replies suggest that these treatments are not effective and recommend medication such as minoxidil or finasteride instead.

      community Why are there no FDA approved NSAA's yet?

      in Research/Science 1 year ago
      The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community FTM/NB Hairloss from HRT, treatment started and feeling hopeless.

      in Transgender  61 upvotes 1 year ago
      A non-binary individual experienced hair loss after stopping hormone replacement therapy and is using oral Dutasteride, oral Minoxidil, and ketoconazole shampoo. They are hopeful for regrowth but may use wigs due to the high cost and uncertain effectiveness of additional treatments like mesotherapy and PRP.

      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  13 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community Finally. Some tangible results. 9mos difference.

      in Progress Pictures  187 upvotes 5 months ago
      The user experienced significant hair improvement over nine months using a routine of oral finasteride, mixed topical and oral minoxidil, microneedling, and Head & Shoulders shampoo. The user attributes the progress to oral minoxidil and reduced stress during paternity leave.

      community Progress pics after 3 years of dutasteride

      in Progress Pictures  33 upvotes 7 months ago
      A 54-year-old user shares progress after 3 years on dutasteride, following 15 years on finasteride, using 0.5 mg/day dutasteride, topical minoxidil every other day, and a peptide serum on alternate days. They experienced a significant shed during the transition but are now maintaining hair, noticing some new growth along the hairline.

      community My 4 month Progress on finasteride

      in Progress Pictures  345 upvotes 10 months ago
      The conversation discusses hair regrowth progress using finasteride, with suggestions to add minoxidil and microneedling for better results. The user experienced noticeable improvement and plans to consider a hair transplant.

      community Hydrophobic Finasteride. Why don’t we have it?

      in Chat  7 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community Update: Exactly one year of treatment

      in Progress Pictures  702 upvotes 1 year ago
      The user shared their one-year hair regrowth progress using topical Minoxidil, oral Finasteride, rosemary oil, and a silicone head massager, along with a healthy lifestyle and supplements. They are happy with the results but acknowledge some hair loss is still visible, especially when wet.

      community Hairloss is mentally exhausting

      in Chat  23 upvotes 5 years ago
      The conversation is about the mental toll of hair loss and seeking alternatives to finasteride. Suggestions include using minoxidil, considering pumpkin seed oil, and possibly seeking counseling for body dysmorphic disorder.

      community 25M - 1.6 years on treatment (diffuse thinning)

      in Progress Pictures  268 upvotes 3 months ago
      A 25-year-old male has been using 0.5mg dutasteride and 5mg minoxidil for 1.6 years to treat diffuse thinning, with significant hair regrowth except for the hairline. He plans to get a hair transplant for further improvement and reports no side effects from the treatment.

      community Stopping fin after 1.8 Years??!!

      in Finasteride/Dutasteride  10 upvotes 4 months ago
      The user is considering stopping finasteride after 1.8 years due to concerns about side effects and is exploring alternatives like minoxidil and topical finasteride. They are also considering microneedling and are advised to wait for new treatments like breezula/clascoterone.

      community Am I crazy to combine oral and topical Finasteride?

      in Finasteride/Dutasteride  5 upvotes 7 months ago
      A 24-year-old male combines topical and oral finasteride with minoxidil to combat hair loss, experiencing heavy shedding but no significant side effects. Other users share their experiences with similar combinations, including using dutasteride and ketoconazole, emphasizing that personalized routines can be effective.

      community Switching from Finasteride to RU58841?

      in General  168 upvotes 7 months ago
      The user experienced severe side effects from finasteride, including cognitive and sexual issues, despite its effectiveness for hair growth. They are considering switching to RU58841 and seek insights from others who have made a similar change.

      community Sodium Laureth Sulfate (SLS) in shampoos

       4 upvotes 10 years ago
      Sodium Laureth Sulfate (SLS) in shampoos and its potential impact on thinning hair. The user follows a regimen of shampoo, keto shampoo, and conditioner, seeking suggestions for better products.

      community Is it good idea to order topical fin from India?

      in Finasteride/Dutasteride  8 upvotes 1 month ago
      A user is considering ordering topical finasteride from India due to unavailability in their country and previous side effects from oral finasteride. Users recommend Indian brands like Morr-F and Minscalp F, noting their affordability and effectiveness, while advising to ensure purchases are from reputable sources.

      community Do dut and fin reduce sebum causing frizzy hair?

      in Finasteride/Dutasteride  6 upvotes 3 weeks ago
      The user is experiencing dry, frizzy hair despite using dutasteride and finasteride for hair loss, which may be due to reduced sebum production. Suggestions include using nourishing conditioners, hair oils, and styling products to manage frizz, especially for curly hair.

      community PRP with Exosomes - The next step for me?

      in Treatment  3 upvotes 4 weeks ago
      The user is considering PRP with exosomes for hair loss after oral minoxidil and dutasteride failed to provide desired results. Despite suggestions for a hair transplant, the user is hesitant due to cost and complexity, and is unsure about other options.

      community Custom topical solution in Bangkok

      in Finasteride/Dutasteride  3 upvotes 6 months ago
      A 28-year-old male uses custom-compounded topical solutions with Minoxidil, Finasteride, and Tretinoin for hair loss maintenance. He seeks advice on sourcing similar solutions in Bangkok, Thailand, and whether a local prescription is needed.